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When RNA processing machinery adjustments happen, disease may result. Alternative splicing, also known as differential splicing, is a process where the RNA exons of the RNA that is produced by transcription of a gene are reconnected in a number of different ways during RNA splicing. If the intron that is retained is located within the coding region, the intron has to encode amino acids in body with the exons that are neighboring, or a shift or stop codon in the reading frame will trigger a non-functional protein. The completely different mRNAs that are created, may be translated, through transcription, into completely different protein isoforms, ensuing in just one gene that could code for a number of proteins. In regular people, the ABCA12 gene encodes a protein, a sort of ATP-binding cassette reporter protein, that is necessary for the traditional improvement of skins cells. When compare